I also use the sculpt Jess recommended - have one at home and at work. I can't type at all with my arms straight so either need an ergonomic keyboard or my wrists are at a 45 degree angle and all the problems that brings.
I find the mouse that comes with it really useful - fits my hand neatly although it is definitely right handed so be wary if you like to use your left hand to drive the mouse.
I did a more in depth review on my blog:
Would heartily recommend although there are a few niggles to be aware of:
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