No. The point of Svelte is that it is compiled up front, meaning the browser has less work to do. That's a core principle of how Svelte works.
As for how easy it is to use with other libs, I use Bulma, various vanilla js libraries and plugins, and they all work a lot more smoothly than they do with other frameworks or libraries. Svelte hinders you less when it comes to playing nice with other things.
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