my two cents:
I think the vocabulary in tailwind is quite extensive. So that a higher entry barrier than e.g. with bootstrap (the css only part of bootstrap). However, for very common and straight forward websites that might fit perfectly it's place. In enterprise applications very often you end up writing pretty custom css, where the tailwind approach would be totally counter practicable.
Also personally I'd like to keep my markup clean, but with tailwind I'm ending up with 'polluted' markup where the styles detail are basically everywhere. So shuffling around the layout e.g. with css themes, without markup changes, becomes pretty hard.
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