I've been a professional C, Perl, PHP and Python developer.
I'm an ex-sysadmin from the late 20th century.
These days I do more Javascript and CSS and whatnot, and promote UX and accessibility.
The problems with non-semantic frameworks are pretty well-documented. Having a set of utility classes like big 10pxpadding widemargin blacktext otherspecificthing in your HTML is not better than using inline styles. If your website has - for example - a Christmas takeover where things are restyled to be red and green and festive, you're in for a long, boring job rewriting all your components.
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The problems with non-semantic frameworks are pretty well-documented. Having a set of utility classes like
big 10pxpadding widemargin blacktext otherspecificthing
in your HTML is not better than using inline styles. If your website has - for example - a Christmas takeover where things are restyled to be red and green and festive, you're in for a long, boring job rewriting all your components.