Actually all interruptions cause disruption, but, as the cartoon shows, what happens to programmers is that they carry a lot of information in their short-term memory when analyzing a problem. The more information you are carrying in your short-term memory, the more difficult is going to recover from an interruption. So, yes, you could do sales, writing, analysis or many other things, but I think that for programmers or people doing math, chemistry or similar things is going to be worse than for a person writing a paragraph of literature, for example. Unless they overloaded their short term memory with a lot of information.
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