Flask with OPC Server

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Hello Everyone, I am new to Python / Server development but experienced with PLC. I would like to create a Flask Python server to serve for a Mobile App / Web server as visualization for Data from PLC. I do not know how to connect Flask Server with another script and to exchange Data between it in full duplex. Is it possible to do it over Sqlite ? Can I write / read a data to the same DB from 2 scripts / servers ? I draw some explanation of my problem (first picture is a problem and a second one may be the possible solution ?/ thanks in advance for your experienced suggestions)

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