A 100 0001 T 101 0100 C 100 0011 G 100 0111
---- -|-- - this bit always changes
---- -|--
---| ---| - this bits only changes when ---- --|- is set to 0
---| ---|
---- --|-
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---- -|--
- this bit always changes---| ---|
- this bits only changes when---- --|-
is set to 0