My greatest problem with infinite scroll is that it breaks URLs. When you have pagination, elements shift around as content gets added, but you can still send someone a link or save a page, and when you open it the next day, you may need to advance a page to get to the content you wanted, but with infinite scrolling you completely lose that hability and instead have to scroll to the desired position each and every time you load a page.
I really think infinite scrolling should be either an easy to opt out feature, or even an opt-in feature for some types of page.
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